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BDNF (Brain-Derived Neurotrophic Factor) ELISA Assay Kit is an Enzyme Immunoassay kit for the quantification of Human BDNF in serum, plasma, or cell culture supernatants. The Brain-Derived Neurotrophic Factor (BDNF) ELISA Assay Kit is for research use only and should not be used for diagnostic procedures.

It is a secreted protein with a molecular weight of 27.8 kDa, consisting of 247 amino acids. It is known to promote the survival and differentiation of neurons. BDNF shares a significant amino acid sequence identity with nerve growth factor (NGF). There are many companies available that provide the best bdnf elisa kit online.

The protein encoded by this gene belongs to the nerve growth factor family. It is induced by cortical neurons and is required for the survival of striatal neurons in the brain.

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Expression of this gene is reduced in Alzheimer's and Huntington's patients. These genes may play a role in the regulation of stress responses and in the biology of mood disorders. Many transcript variants encoding various isoforms have been described for this gene.

During development, BDNF promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding, and modulation of dendritic growth and morphology. An important regulator of synaptic transmission and plasticity in adult synapses in many regions of the CNS.

The universality of BDNF is underscored by its contribution to a variety of adaptive neural responses, including long-term potentiation (LTP), long-term depression (LTD), some forms of short-term synaptic plasticity, and homeostatic regulation of intrinsic neural excitability. 

Occasionally, during shipping and storage, small amounts of BDNF Elisa kit vials may enter the product vial seal.